Thilo

  • 99 contre 1
    Tu es  Bob  « Cold Blood »  Cooper, le meilleur combattant de ton clan. Tu es une véritable machine de guerre, et tu te distingues par ton sang-froid et ton esprit vif.      Ton chef de clan, Marcellus, t'a donné une carte, un chargeur de munitions un peu spécial... et une mission secrète. Tu vas devoir prendre le contrôle de  Dark  Dagalur. Sans quoi, l'humanité n'aura plus jamais accès à ce territoire. Mais tu seras seul. Seul, contre 99 hommes. Fais les bons choix si tu veux être à la hauteur de ta réputation.

  • Mission évasionTu es  Bob  « Cold Blood »  Cooper, le meilleur combattant de ton clan. Tu es une véritable machine de guerre, et tu te distingues par ton sang-froid et ton esprit vif.   
      Ton chef de clan a été enlevé. Il est retenu prisonnier dans la zone industrielle de la  Faded  Factory. A toi d'aller le délivrer. Mais fais les bons choix si tu ne veux pas finir K.O.

  • 1894. Des astronomes sont témoins d'étranges activités à la surface
    de Mars, comme des éclairs ou des explosions de gaz incandescent. Des
    météores venant de la planète rouge se dirigent bientôt vers la
    Terre. Des cylindres s'écrasent et libèrent des engins mécaniques
    contrôlés par des créatures tentaculaires installées à l'intérieur.
    Ces tripodes, armés de leur rayon ardent et d'un gaz toxique appelé
    « fumée noire », se dirigent vers Londres en désintégrant tout sur
    leur passage. L'armée britannique réplique. Mais rapidement, la
    lutte tourne à l'avantage des envahisseurs. Commence alors une fuite
    dans un monde ravagé...

  • Voler comme un faucon, nager comme une raie, courir comme un guépard, grimper comme un gecko... les Animal Heroes sont des super-héros qui tirent leurs pouvoirs des animaux qui les accompagnent. Et ils ont en leur possession une sculpture de serpent maya aux pouvoirs magiques que les terribles Beast Boys veulent à tout prix leur dérober !
    Pablo, onze ans, est un garçon tout à fait comme les autres lorsque, un jour, il se rend compte qu'il peut voler quand il est en présence d'Horus, son faucon. Mais parviendra-t-il, avec l'aide des autres Animal Heroes, à sauver Mojo et son guépard, prisonniers des terrifiants Beast Boys ? Dans les hauteurs des Andes, ils vont se lancer dans une fabuleuse aventure aux nombreux rebondissements !

  • Voler comme un faucon, courir comme un guépard, grimper comme un gecko, nager comme une raie...
    Pablo, Mojo, John et Aiko sont les Animal Heroes et tirent leurs super-pouvoirs des animaux qui les accompagnent !
    John est un excellent nageur qui peut respirer sous l'eau quand il est connecté à sa raie. Mais que peut-il entreprendre, seul face aux Beast Boys ? Perdu au beau milieu de l'Atlantique, il a besoin de l'aide de ses amis...

  • This book provides a comprehensive introduction to the methods and variety of Kelvin probe force microscopy, including technical details. It also offers an overview of the recent developments and numerous applications, ranging from semiconductor materials, nanostructures and devices to sub-molecular and atomic scale electrostatics.In the last 25 years, Kelvin probe force microscopy has developed from a specialized technique applied by a few scanning probe microscopy experts into a tool used by numerous research and development groups around the globe. This sequel to the editors' previous volume "Kelvin Probe Force Microscopy: Measuring and Compensating Electrostatic Forces," presents new and complementary topics.It is intended for a broad readership, from undergraduate students to lab technicians and scanning probe microscopy experts who are new to the field.

  • This book provides an in-depth analysis of "Mega-Regionals", the new generation of trans-regional free-trade agreements (FTAs) currently under negotiation, and their effect on the future of international economic law. The main focus centres on the EU-US Transatlantic Trade and Investment Partnership (TTIP), the Trans-Pacific Partnership (TPP) and the EU-Canada Comprehensive Economic and Trade Agreement (CETA), but the findings are also applicable to similar agreements under negotiation, such as the Regional Comprehensive Economic Partnership (RCEP).The specific features of Mega-Regional Trade Agreements raise a number of issues with respect to their potential effect on the current system of international trade and investment law. These include the consequences of Mega-Regionals for the most-favoured-nation (MFN) principle, their relation to the multilateral system of the World Trade Organization (WTO), their democratic legitimacy and their interaction with existing bilateral investment treaties (BITs).The book is intended for academics and practitioners working in the field of international economic law.

  • Das Buch bündelt aktuelle Fakten zur molekularen Allergologie und zeigt ihre Vorteile für die moderne Allergiediagnostik. Zunächst werden die wichtigsten Proteinfamilien mit Allergenen ähnlicher Struktur vorgestellt. Einzelallergene verbessern vor allem die Treffsicherheit von IgE-Bestimmungen, deren Testvarianten ausführlich erläutert werden. Anhand häufiger Allergenquellen - Inhalations-, Nahrungsmittel- und Insektengiftallergene - werden dann Nutzen und Grenzen einer molekularen Allergiediagnostik im klinischen Alltag aufgezeigt. Der letzte Abschnitt stellt potenzielle Anwendungen der molekularen Allergologie vor, z. B. die Entwicklung rekombinanter Allergenvakzine oder hypoallergener Nahrungsmittel. Das Buch erweitert die erfolgreiche Beitragsserie "Im Fokus: Molekulare Allergologie" aus dem Allergo Journal von Springer Medizin und beschreibt die junge Disziplin der molekularen Allergologie als ein sich rasch entwickelndes Fachgebiet. Dabei liefert es wertvolle Hinweise für die Umsetzung im klinischen Alltag und hilft, die Diagnostik, Beratung und Versorgung allergischer Patienten zu verbessern. 

  • This book, based on a recent German publication, offers an overview of basic data and recent developments in the groundbreaking field of molecular allergology. It comprehensively explores the origin and structure of single allergen molecules ("components") and their utility in improving the management of type I, IgE-mediated allergic reactions and disorders like allergic respiratory diseases, food allergies, and anaphylaxis. Highly specific testing, called component-resolved diagnostics, aims to identify and utilize single molecules. Over 200 single allergens from plant or animal sources have been applied to single or multiplex laboratory testing for the presence of allergen-specific IgE. This leap in assay sensitivity and specificity has led to three major advances in patient management: discrimination between primary allergic sensitization and complex cross-reactivity, recognition of IgE profiles for certain allergens and identification of patients most likely to benefit from allergen-specific immunotherapy. The book discusses in detail the benefits and limitations of this 21st century technology, and offers suggestions for the use of molecular allergology in routine clinical practice. It is a "must read" for physicians treating allergic patients as well as scientists interested in natural allergic molecules and their interactions with the human immune system.

  • Component Models and Systems for Grid Applications is the essential reference for the most current research on Grid technologies. This first volume of the CoreGRID series addresses such vital issues as the architecture of the Grid, the way software will influence the development of the Grid, and the practical applications of Grid technologies for individuals and businesses alike.
    Part I of the book, "Application-Oriented Designs", focuses on development methodology and how it may contribute to a more component-based use of the Grid. "Middleware Architecture", the second part, examines portable Grid engines, hierarchical infrastructures, interoperability, as well as workflow modeling environments. The final part of the book, "Communication Frameworks", looks at dynamic self-adaptation, collective operations, and higher-order components.
    With Component Models and Systems for Grid Applications, editors Vladimir Getov and Thilo Kielmann offer the computing professional and the computing researcher the most informative, up-to-date, and forward-looking thoughts on the fast-growing field of Grid studies.

  • This book has two main goals: to define data science through the work of data scientists and their results, namely data products, while simultaneously providing the reader with relevant lessons learned from applied data science projects at the intersection of academia and industry. As such, it is not a replacement for a classical textbook (i.e., it does not elaborate on fundamentals of methods and principles described elsewhere), but systematically highlights the connection between theory, on the one hand, and its application in specific use cases, on the other.  
    With these goals in mind, the book is divided into three parts: Part I pays tribute to the interdisciplinary nature of data science and provides a common understanding of data science terminology for readers with different backgrounds. These six chapters are geared towards drawing a consistent picture of data science and were predominantly written by the editors themselves. Part II then broadens the spectrum by presenting views and insights from diverse authors - some from academia and some from industry, ranging from financial to health and from manufacturing to e-commerce. Each of these chapters describes a fundamental principle, method or tool in data science by analyzing specific use cases and drawing concrete conclusions from them. The case studies presented, and the methods and tools applied, represent the nuts and bolts of data science. Finally, Part III was again written from the perspective of the editors and summarizes the lessons learned that have been distilled from the case studies in Part II. The section can be viewed as a meta-study on data science across a broad range of domains, viewpoints and fields. Moreover, it provides answers to the question of what the mission-critical factors for success in different data science undertakings are.  The book targets professionals as well as students of data science: first, practicing data scientists in industry and academia who want to broaden their scope and expand their knowledge by drawing on the authors' combined experience. Second, decision makers in businesses who face the challenge of creating or implementing a data-driven strategy and who want to learn from success stories spanning a range of industries. Third, students of data science who want  to understand both the theoretical and practical aspects of data science, vetted by real-world case studies at the intersection of academia and industry.

     

  • This book attempts to establish how courts of general jurisdiction differ from specialized human rights courts in their approach to the implementation and development of international human rights. Why do courts of general jurisdiction face particular problems in relation to the application of international human rights law and why, in other cases, are they better placed than specialized human rights courts to act as guardians of international human rights? At the international level, this volume focusses on the International Court of Justice and courts of regional economic integration organizations in Europe, Latin America and Africa. With regard to the judicial implementation of international human rights and human rights decisions at the domestic level, the contributions analyze the requirements set by human rights treaties and offer a series of country studies on the practice of domestic courts in Europe, the Americas, Africa and Asia. This book follows up on research undertaken by the International Human Rights Law Committee of the International Law Association. It includes the final Committee report as well as contributions by committee members and external experts.

  • Patents protecting biotechnological invention are becoming ever more important. Because biotechnology has many differences with respect to other technologies, lessons learned in other fields of technology cannot simply be transferred to adopt a suitable strategy for dealing with biotechnology inventions. In this volume, general aspects of biopatent law will be discussed. This involves questions of patentability, including ethical issues and issues of technicality, as well as questions of patent exhaustion in cases were reproducible subject matter, like cells or seeds, is protected. Moreover, active and passive patent strategies are addressed. Further, insight will be given into patent lifetime management and additional protective measures, like supplementary protection certificates and data exclusivity. Here, strategies are discussed how market exclusivity can be extended as long as possible, which is particularly important for biopharmaceutical drugs, which create high R&D costs.

  • This book provides an overview of network science from the perspective of diverse academic fields, offering insights into the various research areas within network science. The authoritative contributions on statistical network analysis, mathematical network science, genetic networks, Bayesian networks, network visualisation, and systemic risk in networks explore the main questions in the respective fields: What has been achieved to date? What are the research challenges and obstacles? What are the possible interconnections with other fields? And how can cross-fertilization between these fields be promoted?

    Network science comprises numerous scientific disciplines, including computer science, economics, mathematics, statistics, social sciences, bioinformatics, and medicine, among many others. These diverse research areas require and use different data-analytic and numerical methods as well as different theoretical approaches. Nevertheless, they all examine and describe interdependencies, associations, and relationships of entities in different kinds of networks.

    The book is intended for researchers as well as interested readers working in network science who want to learn more about the field - beyond their own research or work niche. Presenting network science from different perspectives without going into too much technical detail, it allows readers to gain an overview without having to be a specialist in any or all of these disciplines.

  • Im Praxisbuch für Physio- und Ergotherapeuten sind die Grundlagen für die Untersuchung und Behandlung der oberen Extremität bei orthopädischen/neurologischen Verletzungen und Pathologien umfassend dargestellt: von der Anatomie über Biomechanik, Wundheilungsphasen, Clinical Reasoning bis hin zur Bewertung von Assessment-Tools und Tests. Der Praxis-Teil bietet Anleitungen für Basisuntersuchung und Befundung. Behandlungskonzepte und Strategien der postoperativen Nachbehandlung werden beschrieben - jeweils illustriert mit Beispiel-Protokollen.

  • This book assesses recent migration patterns in Europe, which have significantly included 'return migration' against the stream of East-West migration. Since the Eastern enlargement of the EU, many regions of Central and Eastern European have experienced a loss of human resources in core industries, raising concerns about social, economic and territorial cohesion in the region. The success rates of national and regional governmental policy aiming to retain or re-attract skilled workers have been variable, yet return migration has emerged as a major element of migration flows.
    Bringing together leading researchers on this important topic in contemporary European geography, the contributors analyse a series of key issues. These include: theoretical frameworks in the field of return migration; the nexus between return migration and regional development; the effects of the global and European crisis on emigration and return migration; non-economic motivations for emigration and return; the intergenerational character of return migration, and; the reintegration of return migrants into post-socialist societies. Taken together, the chapters see return migrants as important agents of change, innovation and economic growth. The book will be of great interest for scholars and students of human, economic and political geography.

  • Der Autor untersucht die Regelungen der
    39a und 39c WpÜG unter besonderer Berücksichtigung praktischer Gesichtspunkte. Bei der Durchführung eines Übernahmeverfahrens nach dem WpÜG kommt es regelmäßig zu Herausforderungen, insbesondere, wenn die vollständige Übernahme der Zielgesellschaft beabsichtigt wird. Die vom Gesetzgeber hierfür geschaffene Sonderregelung wird von der Praxis jedoch bislang kaum angenommen und weist deutliche Schwächen auf. Gegenstand der Untersuchung ist es, diese Schwächen der gesetzlichen Regelung de lege lata herauszuarbeiten und de lege ferenda einer Lsung zuzuführen.

  • In this publication a widespread phenomenon is studied: in many usage scenarios modern complex machines show a significant difference between the maximum sustainable performance available in well specified environments and the average performance many users experience in their everyday interaction with the machine. This performance gap appears to be increasing with technical progress and performance of machines. Although this situation is probably well known to many readers -- and very often not so quietly endured -- it was not studied systematically so far. This publication describes the conceptual background of the performance gap in a very general way. It develops a semi-quantitative description and points to approaches to reduce the performance gap in current and future environments. Process executives, engineers and system analysts will hopefully benefit from this approach especially in the dynamic environments envisioned in initiatives like the German Industrie 4.0. 
    In the technology network Intelligent Technical Systems OstWestfalenLippe (short: it's OWL) around 200 companies, universities, research institutions and organisations have joined forces to jointly shape the innovative leap from mechatronics to intelligent technical systems. Together they develop approaches and technologies for intelligent products and production processes, smart services and the working world of the future. The spectrum ranges from automation and drive solutions to machines, vehicles, automats and household appliances to networked production plants and platforms. This creates a unique technology platform that enables companies to increase the reliability, resource efficiency and user-friendliness of their products and production systems and tap the potential of digital transformation.

  • Die Arbeit gibt einen Überblick über theoretische Konzepte und empirische Ergebnisse aus dem Arbeitsfeld Kriminalgeographie (Wohn- und Tatorte), einem Bereich der Sozialgeographie. Die Konzepte kommen aus der Sozialgeographie, der Umwelt- bzw. Ökopsychologie und der Sozialkologie, einem Forschungsbereich der Stadtsoziologie. Kriminologisch relevante Theorien mit räumlichem Bezug bilden eine theoretische Brücke zu diesen Konzepten. Die empirischen Ergebnisse hierfür wurden Studien über Städte entnommen. Der Schwerpunkt der Darstellung liegt im theoretischen Bereich, doch auch die empirischen Daten führen zu präventiv nutzbaren Konzepten durch Umweltgestaltung, d. h. Architektur und Stadtgestaltung, und sozialstrukturelle Maßnahmen, wie die Belegungspraxis von Wohnbaugesellschaften. Ziel ist die Erhhung der sozialen Kontrolle in Problemvierteln und die Sicherung von Tatorten.

  • Despite the emphasis of the European Regional Policy on territorial cohesion, regional disparities have been increasing within Europe in the past years. The metropolitan areas in almost all countries are considerably growing while regions outside of agglomerations are stagnating or even declining. Against this background this book aims to provide an understanding of the underlying processes of polarisation and related regional and local policies.
    This open access volume contributes to the debates about polarisation and regional development by focussing on questions of spatial justice, power distribution and policy transfer. Theoretical and empirically grounded contributions show that European policies are indeed reproducing socio-spatial inequalities instead of challenging them. The book shows further the existing potentials and limits of individuals, economic, political and civil society actors to respond to polarisation on the regional and local level.
    In this book conceptual thoughts on polarisation, regional policy and regional development are combined with empirical research and resulting implications for policymaking. As such, it is a valuable source for early career students and researchers as well as professionals in the field of regional and economic development, policy consultants, and policy makers.

  • Um ihre angestrebten, betragsmäßig häufig erheblichen Investitionsziele realisieren zu knnen, greifen Fußballunternehmen immer häufiger auf Fan- oder Mittelstandsanleihen zurück. Meist führt die emotionale Bindung eines Fans zu seinem Verein dazu, dass die aus der Anleihe erwarteten Renditeziele nicht das Ergebnis rationaler Überlegungen sind, sondern dass vielmehr die Anschaffung solcher Anleihen auf den intrinsischen Motiven der Anhänger basiert und einer Anleihe eine ähnliche Wertschätzung zuteil wird wie etwa Merchandising-Produkten. Die aus Fan-Motiven geleitete Anlageentscheidung hat damit unmittelbar Einfluss auf die zukünftige Vermgenssituation des Gläubigers. Der Autor gibt einen Überblick über die in Deutschland begebenen Fußballanleihen und beschreibt unter anderem die Hintergründe, die technische Abwicklung und die Vermarktung von Fußballanleihen. Für die zweite Auflage wurde das Essential aktualisiert.

  • Auf Basis theoretischer und empirischer Analysen entwickelt Isabelle Thilo ein internes Markenführungsmodell für Destinationen. Im Rahmen ihrer Untersuchung analysiert sie die Einflussfaktoren der relevanten Zielgrßen sowie die Fragestellung, wie sich die Forderung nach Identifikation der internen Anspruchsgruppen, z. B. aus Hotellerie und Gastronomie, mit der Marke und der Umsetzung in markenkonformes Verhalten in der Praxis realisieren lassen. Hierzu verdeutlicht sie die Relevanz der Kooperation mit den Stakeholdern und zeigt Ansätze zur Implementierung der Prämissen der identitätsorientierten Markenführung in das Destinationsmanagement auf. Denn steigender Wettbewerbsdruck sowie die Zielsetzung, sich mittels einer starken Marke zu profilieren, bestimmen auch die Tourismusbranche und die Handlungsweisen ihrer Akteure.

  • Peter Thilo Hasler gibt einen umfassenden Überblick über die Finanzierung von Fußballunternehmen am Kapitalmarkt durch Aktien oder Anleihen. Er schildert ausführlich, warum das häufig gegen Fußballaktien vorgebrachte Argument, wonach sportliche Erfolge für den Aktienkurs von hherer Bedeutung sind als wirtschaftliche Ereignisse, nicht gegen, sondern vielmehr für diese Asset-Klasse spricht. Ergänzt werden die Ausführungen durch detaillierte Informationen zu rechtlichen Vorschriften, Brsennotierung, Zeichnung und technischer Abwicklung im Zusammenhang mit der Begebung von Fußballanleihen und -aktien.

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